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Selegiline Hydrochloride (compare to Anipryl) rx

Selegiline Hydrochloride (compare to Anipryl) rx


What is Selegiline?

Selegiline, also known as L-Deprenyl, is a monoamine oxidase inhibitor (MAOI) that treats Cushing's Disease and Canine Cognitive Dysfunction Syndrome (senility). Selegiline requires a prescription from your veterinarian.




  • Easy to administer
  • Once a day dosing


Selegiline should not be given if the pet is taking meperidine. Tell your veterinarian about any other medical conditions your pet has. Tell your veterinarian if your pet is pregnant or lactating. Because Selegiline belongs to a class of drugs called Monoamine Oxidase Inhibitors (MAOI) it should not be given with antidepressants such as Prozac. Make sure you tell your veterinarian what other medications you are giving your pet. Selegiline may cause dizziness or drowsiness. Do not give higher doses than those prescribed.

Brand Name:

Anipryl (Pfizer Animal Health)

Generic Name:

Selegiline (see-ledge'-a-leen)

What happens if I miss giving a dose:

If a dose of Selegiline is missed, give the dose as soon as possible. If it is almost time for the next dose, skip the missed dose and continue your regular schedule. Do not give two doses at one time

Possible side effects of Selegiline:

If any serious side effects occur (difficulty breathing, hives, agitation, swelling of the lips, tongue or face), stop giving Selegiline and seek emergency veterinary care. Continue giving selegiline and talk to your veterinarian if your pet develops dizziness or drowsiness, nausea, abdominal pain or diarrhea, insomnia, mild confusion, agitation or anxiety, dry mouth.


Store this product at room temperature, away from moisture and heat.


Give this medication exactly as directed by your veterinarian. Have plenty of water available for your pet to drink. Do not give more of this medication than is prescribed without consulting your veterinarian. Selegiline may cause drowsiness or dizziness.


Dogs: (when used for cognitive dysfunction)
All weightsThe starting dose for canine cognitive dysfunction is 0.2mg-0.45mg per pound of pets body weight. It may take up to one month or more to see improvement

Dogs: (when used for Cushing's disease)
All weightsThe usual starting dose to treat Cushing's disease is 0.45mg per pound of pets body weight given once a day in the morning. If no result within two months, may increase to 0.9mg per pound of pets body weight. If still no response after one month of the increased dose, your pet should be reevaluated.

Do not use!

Do not use!

Active Ingredient
Selegiline hydrochloride, USP5 mg
Other Ingredients: Citric Acid, Anhydrous Lactose, Magnesium Stearate, and Microcrystalline Cellulose.
  • Easy to administer
  • Once a day dosing


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