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Advantage Multi for Cats rx


Advantage Multi for Cats is a once-monthly topical product that controls and treats intestinal parasites like roundworm and hookworm, controls and treats ear mites, treats existing flea infestations, kills adult fleas, and prevents heartworm disease.


For use in kittens (ages 9 weeks and up; 2 pounds or greater) and cats.


  • Controls and treats ear mites
  • Treats flea allergy dermatitis (FAD)
  • Controls and treats roundworms and hookworms
  • Controls and treats flea infestations
  • Prevents heartworm disease


Bayer Animal Health

Active ingredient(s):

imidacloprid + Moxidectin

Potential side effects include:

  • Coughing
  • Increased water consumption
  • Increased salivation for an hour following treatment
  • Application site discomfort (scratching, rubbing, etc.)
  • Pacing
  • Hiding
  • Excessive grooming
  • Agitation
  • Prolonged periods of sleep
  • Lethargy

If the cat licks the site of application or if the medication is accidentally orally administered, the following reactions may occur:

  • Decreased appetite
  • Vomiting
  • Tremors
  • Increased salivation


  • Do not ingest orally.
  • Never apply to irritated skin.

In case of overdose:

Contact your closest emergency pet hospital.


Avoid heat or cold. Store between 4°C (39°F) and 25°C (77°F).

The recommended minimum dose is 4.5 mg/lb (10.0 mg/kg) imidacloprid and 0.45 mg/lb (1.0 mg/kg) moxidectin, once a month, by topical administration.

Do not apply to irritated skin.

1. Remove one dose applicator tube (tube) from the package. As specified in the following table, administer the entire contents of the Advantage Multi® for Cats tube that correctly corresponds with the body weight of the cat.    

* Cats over 18 lbs. should be treated with the appropriate combination of Advantage Multi for Cats

2. While holding the tube in an upright position, remove the cap from the tube.

3. Turn the cap over and push the other end of cap onto the tip of the tube.

4. Twist the cap to break the seal and then remove cap from the tube.

5. Part the hair on the back of the cat’s neck at the base of the head, until the skin is visible. Place the tip of the tube on the skin and apply the entire contents directly on the exposed skin. Lift tube away from skin before releasing pressure on tube.

Do not get this product in the cat’s mouth or eyes or allow the cat to lick the application site for 30 minutes. Treatment at the base of the head will minimize the opportunity for ingestion by grooming. In households with multiple pets, keep animals separated to prevent licking of the application site.

Stiff, matted hair or a damp, oily appearance of the hair may be observed at the application site on some cats. This is temporary and does not affect the safety and effectiveness of the product.

For 30 minutes following application, monitor the cat to be sure that they cannot lick the application site and ingest product from other treated cats or themselves. Treated cats should be separated from each other and from any other pets in the home to diminish the risk of accidentally ingesting.

Main Ingredients:

Advantage Multi for Cats (10% imidacloprid + 1% moxidectin) is a colorless to yellow ready-to-use solution packaged in single-dose applicator tubes for topical treatment of cats.
Imidacloprid is a chloronicotinyl nitroguanidine insecticide. The chemical name of imidacloprid is 1-[(6-Chloro-3-pyridinyl)methyl]-N-nitro-2-imidazolidinimine. Moxidectin is a semisynthetic macrocyclic lactone endectocide derived from the actinomyceteStreptomycetes cyaneogriseus noncyanogenus. The chemical name of moxidectin is [6R, 23E, 25S(E)]-5-O- Demethyl-28-deoxy-25-(1,3-dimethyl-1-butenyl)-6,28-epoxy-23-(methoxyimino) milbemycin B.


  • Controls and treats ear mites
  • Treats flea allergy dermatitis (FAD)
  • Controls and treats roundworms and hookworms
  • Controls and treats flea infestations
  • Prevents heartworm disease


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