Zenrelia is an innovative prescription medication and once daily treatment to break the itch-scratch cycle that lets dogs get back to normal life. Zenrelia is used for treatment in controlling pruritus associated with allergic dermatitis and control of atopic dermatitis in dogs at least 12 months of age. Zenrelia is an immunosuppressant that is administered orally, once daily, with or without food.

Benefits:

• Works fast.
• Optimized dosing, no loading or tapering, just once a day from the start.
• Minimizes chances for rebound of itch and allergies.
• Continuous efficacy.
• Improves skin condition by reducing lesions and inflammation.
• Used as long term relief for maintenance therapy.

For:

For oral use in dogs only.

Sold As: 

Zenrelia (ilunocitinib tablets) is available in scored tablets in four strengths: 4.8 mg, 6.4 mg, 8.5 mg, and 15 mg. 

Manufacturer:

Elanco

Dosage:

The dose of Zenrelia (ilunocitinib tablets) is 0.27 to 0.36 mg ilunocitinib/lb (0.6 to 0.8 mg ilunocitinib/kg) body weight, administered orally, once daily, with or without food.

Safety:

Zenrelia is a JAK inhibitor approved by the FDA in September of 2024 for control of pruritus associated with allergic dermatitis and control of atopic dermatitis in dogs at least 12 months of age.

Caution:

Not for use in humans. Keep this drug out of the reach of children, dogs, cats and animals to avoid accidental ingestion. Wash hands immediately after handling tablets. In case of accidental ingestion, seek medical attention immediately.

Side Effects:

In clinical trials, most observed adverse events were vomiting, diarrhea and lethargy.

Precautions:

Discontinue Zenrelia for at least 28 days to 3 months prior to vaccination and withhold Zenrelia for at least 28 days after vaccination. Dogs should be up to date on vaccinations prior to starting Zenrelia. The safe use of Zenrelia has not been evaluated in breeding, pregnant, or lactating dogs. Decreased prostate gland weights in intact male dogs were observed in a laboratory safety study. The safe use of Zenrelia has not been evaluated in combination with glucocorticoids, cyclosporine, or other systemic immunosuppressive agents.

Storage:

Store at room temperature between 15 to 25°C (59 to 77°F), excursions permitted between 5 to 40°C (41 to 104°F).